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Testing Scaffolds for Bone Replacement

Testing Scaffolds for Bone Replacement

Research into biomaterials requires the test environment to correspond to actual conditions as far as possible. For this reason testing in this field is preferably carried out in fluid baths or complete incubators. In this application, cells from bone marrow are applied to a carrier material and cultivated in a liquid nutrient under cyclic mechanical stimulation. For this an ambient temperature of 37 °C, 100% humidity and cyclic loading (using Zwick testing actuator) under very low forces are necessary. The load is applied to the specimen via a die integrated into the incubator from above and the specimens immersed in the liquid nutrient are flushed with CO2 or N2 to adjust the pH value. Extensions lie between 30 and 100 μm.


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